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John Arnold (JA) and Helen Banwell (HB) for their assistance in undertaking the database searches.
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A systematic search was undertaken in the databases Medline, Embase, PsycINFO, SveMed and CINAHL (EBSCO).
A comprehensive literature search was undertaken in the databases of MEDLINE (1950 1 January 2015) (Pubmed), CENTRAL (1800 1 January 2015) (Cochrane Central Register of Controlled Trials), and EMBASE (1966 1 January 2015) by means of a combination of MeSH terms and text words.
Our assessment criteria are shown below and provide a structure that can be used to report the quality and comparability of the included reviews to help readers assess the strength of the evidence in the review of reviews: ▪ The extent of searching undertaken: Are the databases searched, years searched and restrictions applied in the original review clearly described?
JD developed and maintained the Access database; undertook the classification of outcomes and interventions; performed the analyses; contributed to the interpretation; and drafted the manuscript.
To confirm the reliability of our computational prediction, we undertook the N. vitripennis EST database search and found more than 60% peptides have corresponding transcripts, suggesting the genes encoding these peptides are expressed at the transcriptional level.
AWM participated in the design of the study, undertook all database searches, oversaw all aspects of the laboratory work, analyzed the data and prepared the manuscript.
YTC, CJL, and TJC collected the data, organized the database, undertook data analysis, and interpreted the data.
In view of the widespread human exposure to alkylanilines and other evidence summarized in the preceding sections, we have undertaken investigations to expand the database concerning their genotoxicity in mammalian cell systems.
Our validation results confirm earlier studies undertaken on the THIN database (another general practice database which is derived from the Vision system but which is not linked to mortality data).
The highest ranked purposes for which modeling was undertaken were database design and management, business process documentation, business process improvement, and software development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com