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Haplotype analysis was undertaken using the program HAPLOVIEW v4.0.

The analysis was undertaken using SPSS16 and MATLAB.

Most hybrid modelling has been undertaken using annual timesteps.

Sequence analysis was undertaken using the DNASTAR software.

Analyses were undertaken using Epiinfo [15] and SPSS [18].

A retrospective claims analysis was undertaken using the MarketScan® Databases.

All dilutions and reactions were undertaken using deionized water.

Cracking observation is undertaken using digital image correlation.

A computational study was undertaken using the ER theory.

Multi-allele tests were undertaken using haplotypes.

Structural superpositions were undertaken using MultiProt (http://bioinfo3d.cs.tau.ac.il/MultiProt/) [54].

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