Some classifiers have now become commercially available diagnostic tools for breast cancer, making it imperative to understand how they function as well as how they differ from one another.
Although the physiological function of NET formation is incompletely understood, NETs are thought to function as a pro-inflammatory form of cell death, known as NETosis, that links the innate and adaptive immune responses.
To better understand the ability of VCN to function as an anti-metastatic agent, we are currently testing this agent in several spontaneous models of breast cancer metastasis (i.e., the murine 4T1 and D2F2, and human MDA-MB-231).
For West, these questions don't arise, since beyond its scholarly value he understands F1 to function primarily as a simple, universally recognised luxury item or status symbol.
It is important for the prescribing health-care provider to understand device function, as well as the pathophysiology of cardiorespiratory events in different disease states in order to make logical decisions about which monitor to prescribe, or whether to prescribe one at all.
Reproductive isolating mechanisms are generally understood to accumulate gradually as a function of molecular genetic distance, a surrogate for time since divergence [ 8].
A prime challenge in developing such strategies is to understand how genes function as interaction networks to carry out and regulate cellular processes, and how perturbations in these cellular networks cause certain phenotypes, such as human diseases, in some individuals, but not in the others.
Therefore, further studies are necessary to clarify the detailed roles of individual PADs during tumor development and to understand whether they function as tumor suppressors or oncogenes.
In the stem cell field, many efforts are made to dissect the signaling networks regulated by protein phosphorylation in hPSCs and understand how they function as a whole to regulate cellular pluripotency and differentiation.
