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Although the mechanism of DNA damage-induced apoptosis remains poorly understood, the involvement of several pathways in this process have been suggested.
Although the molecular mechanism is not fully understood, the involvement of cytoskeletal proteins in the NF-κB signaling was previously reported.
While the role of other detoxification enzymes in insecticide resistance is well understood, the involvement of proteases/serine proteases is not.
Although the physiological role of MMP-11 is still poorly understood, the involvement of this enzyme in especially the early stages of the process of tumor formation and metastasis has been thoroughly investigated [reviewed in Rio (2005)].
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In this review, we intend to clarify the molecular mechanisms underlying the tumor suppressive functions of p53 and understand the involvement of the p53 signaling pathway in tumorigenesis.
In addition, the effects of inhibitor were studied to understand the involvement of amino acid on the activity of B. stratosphericus lipase.
Further bacteriological studies into the marine environment are needed to understand the involvement of fecal flora contaminating seawater in the pathophysiology of pneumonia associated with drowning.
To understand the involvement of intestinal microflora in the pathogenesis of IBD, we analyzed the constituents of intestinal microflora in IBD.
The results of the SEC analysis after desorption of HA from fungal mycelia (recovery) are most important to understand the involvement of biosorption in the removal of HA by WRF.
The study demonstrated here might be useful to biogeochemical engineer to understand the involvement of heterotrophic bacteria in global biogeochemical cycle and to gain further insight into the diversified application of these microorganisms.
We used transgenic mouse models to help understand the involvement of recruited cells in prostate regrowth.
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