Sentence examples for understanding trial from inspiring English sources

Because understanding the context in which interventions are implemented is imperative for effective pragmatic trials and dissemination and implementation research, the use of mixed methods is critical to understanding trial results and the success or failure of implementation efforts.

For such user-dependent methods, with dosing either at fixed intervals or linked to specific events (such as sex acts), accurate and objective measurements of adherence are critical for understanding trial results, since limited or zero effectiveness of an investigational product may be due to either the product's lack of biological efficacy or sub-optimal user adherence [ 8– 10].

More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review.

The present study was designed to assess the impact on the understanding of trial participants of the essential components of a trial, as well as on the perceptions of the participants, through enrollment via a standard versus a modified informed consent protocol.

5 Although we initially intended to investigate patient understanding of trial results and the preferred method of receiving end-of-trial information, the low response rate makes it difficult to extrapolate findings to the wider population.

We support the suggestions of Shalowitz and Miller (2008) that most informative would be research showing the resource costs and effects on patients of various feedback alternatives, as well as outcomes in terms of satisfaction, understanding, and trial perceptions/behavioural intentions, including willingness to participate again and/or recommend trials to others.

Better understanding of trial participant perspectives on the acceptability of the test product and their experience with it can help implementers optimize adherence as a trial proceeds.

Although the ITT analysis is, and will likely remain, the gold standard for evaluating effectiveness in microbicide trials, adherence-adjusted analyses offer the potential for more powerful tests and richer understanding of trial data and their implications.

The goal of this article is to facilitate the reading and understanding of trial reports and to provide an appreciation of what can and cannot be inferred from clinical trials.

Interviews explored their recall and understanding of trial information, and their reasoning about how they were allocated to a treatment.

Nevertheless, large cohorts of patients were recruited for interventional studies in the last few years which improved our understanding of trial methodology in APDs immensely.