Sentence examples for understanding the structural basis from inspiring English sources
DOI: http://dx.doi.org/10.7554/eLife.00184.013 The structure of GsuK provides an excellent model system for understanding the structural basis of multi-ligand regulation of the RCK gating ring as commonly seen in the eukaryotic Slo channels.
Therefore, we proved that the overall procedure of docking, scoring, and CoMFA evaluation can be a useful tool to validate homology models, which can be of value for structure-based design, in-silico screening, and in understanding the structural basis of ligand binding to MCH1R.
The lack of a structure for any full-length p110/p85 heterodimer has made understanding the structural basis for regulation of p110 by p85 challenging, however, the use of hydrogen deuterium exchange mass spectrometry (HDX-MS) has allowed us to probe p85 regulation of the class IA holoenzymes.
Consequently, understanding the structural basis of their robust mechanical properties is of great interest.
Our analysis provides a structural portrait of the PDZ domain family, which serves as a guide in understanding the structural basis for the diverse specificities across the family.
Understanding the structural basis for this antigenic difference between these antibodies will help direct the design of a broad-spectrum and MSP2-based malaria vaccine.
By understanding the structural and genetic basis of these traits, quality evaluation programs could build upon their current capacity and develop tools to enable evaluation of these traits.
Understanding the structural and molecular basis of mitotic chromosome condensation and segregation remains a basic challenge in cell biology.
Understanding the structural and mechanistic basis for this partial agonism is an important future goal.
Understanding the structural and functional neurobiological basis of this process and how it influences variability in individual outcomes might be important for prognostication and design of future restorative therapies (Krakauer 2005; Nudo 2003; Stinear et al. 2012).
The development of the Icotea basin provides an excellent observational basis for understanding the structural history of three sets of regionally extensive faults and testing two models for the formation of pull-apart basins in general.
