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Understanding the spectrum of CIN genes will allow us to understand the etiology of human diseases associated with genetic instability and ultimately help design strategies to combat these diseases.
It is of paramount importance for the radiologist to be aware of the MRI features because understanding the spectrum of appearances of the various benign cystic lesions is vital for optimal patient management.
While labels can be limiting when explaining and understanding the spectrum of identities and experiences in the LGBTQ community, they certainly are politically and socially useful ― and Merriam-Webster is a key player in giving them mainstream legitimacy.
Natural isolates provide a unique testing ground for understanding the spectrum of biofilm-related phenotypes achieved by S. cerevisiae outside of laboratory strains.
We hope that the presentation of rare cases will contribute to understanding the spectrum of the disease by aiding its clinical identification and pathogenetic understanding.
Understanding the spectrum of sepsis pathophysiology in a heterogeneous human patient population is a necessary first step to redefining this syndrome and individualizing sepsis management [ 8].
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Understanding the full spectrum of effects of lenalidomide and pomalidomide on this important family of transcription factors and additional potentially relevant novel CRL4CRBN substrates is critical for optimal use of these drugs in haematological malignancies, as well as for immunotherapy in oncology and autoimmune/inflammatory diseases.
Understanding the full spectrum of effects of a small molecule could aid in minimizing off-target effects and enhance the design of highly specific drugs.
For example, individuals participating in the qualitative phase described knowledge that had been acquired from attending the play (e.g., understanding about the spectrum of BD and the heterogeneity of experiences).
Escalating human disturbance underscores the importance of understanding the full spectrum of evolutionary impacts that humans are having on natural populations (Smith and Bernatchez 2008; Hendry et al. 2011; Sih et al. 2011).
This presents a missed opportunity in understanding the full spectrum of hantavirus disease, and reduced awareness of where and how persons are exposed to hantaviruses.
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