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The benefits of understanding the molecular changes promoting lung carcinogenesis go beyond drug development.
These data greatly contribute to understanding the molecular changes of LSCs and developing novel therapies for eradicating LSCs and even achieving curable effect of CML.
Understanding the molecular changes within the tumor microenvironment during tumor progression may therefore be relevant not only for discovering potential therapeutic targets, but also for identifying putative molecular signatures that may improve tumor classification and predict clinical outcome.
In recent years, a significant amount of attention has been focused upon understanding the molecular changes underlying the adverse effects of therapeutic radiation which negatively impact a patient's quality of life as a means for developing useful therapeutic interventions.
Understanding the molecular changes underlying phenotypic differences between species is of great biological interest (Hahn et al. 2007).
Although major progress has been made in understanding the molecular changes that characterize epidermal differentiation, less is known about the signalling pathways that control these events.
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Understanding the molecular biological changes underlying the process of epileptogenesis is crucial to the development of newer, more effective treatment regimes.
Therefore, understanding the molecular and functional changes that occur in these neurones in response to variable maternal sensory inputs has been the focus of recent research.
As advanced-stage OSCC has a poor prognosis [ 1], understanding the molecular and biological changes of its progression is critical to development of more effective therapies.
Our study provides a basis for understanding the molecular mechanisms underlying changes in flowering traits in response to cytokinin treatment in J. curcas, and provides useful information on the mechanisms of cross-talk among multiple hormone signaling pathways in woody plants.
Future research will be directed at understanding the molecular basis for observed changes in the epidemiology of NoV and control of its spread.
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