Sentence examples for understanding the hallmarks of from inspiring English sources

In principle, this level of design-based analysis can be applied to any protein, paving the way toward identifying and understanding the hallmarks of the thermodynamic and structural limits of function.

Understanding the molecular hallmarks of this transition has been the target of extensive study by the wider research community.

The list of Parkin substrates continues to grow, although it is not clear which are critical for understanding the death of dopaminergic neurons, the hallmark of Parkinson's disease.

On the other hand, the complex symptoms of AD and their partial correlation with pathological hallmarks indicate that understanding the pathogenesis of AD may require investigations of abnormalities at multiple levels; this would enhance our awareness that various compensatory mechanisms are at work in maintaining brain functions [9].

Increasing understanding of the mechanisms underpinning the hallmarks of cancer have recognised the importance of the tumour microenvironment during tumourigenesis and in response to cancer therapy (Hanahan and Weinberg, 2011).

Furthermore, a hallmark in the process of understanding the etiology of a disease and studying its natural history is the ability to identify and differentiate its various forms and place them into a rational etio-pathologic framework.

Molecular landscapes have been used to help establish the six key defects that are the hallmark of frank carcinogenesis; however, understanding the timing and order of occurrence of these molecular events during the latency period is ongoing.

These four principles provide an evolutionary framework for understanding the origins and progression of cancer that is parallel to what the Hallmarks of Cancer framework (Hanahan and Weinberg 2000) provides for understanding cellular mechanisms involved in cancer.

Anderson, whose understanding of childhood is one of the hallmarks of his art — a point of similarity with Truffaut — builds another axis of drama by giving the Foxes a nephew, a gallant young athlete, and setting him up as a rival to their more idiosyncratic son.

Elucidation of these mechanisms is essential for understanding the molecular basis of the cell and species specificity which is a hallmark of TCDD toxicity.

First comes understanding the value of doubt.