Sentence examples for understanding the functional impact from inspiring English sources

It could be an important tool to understanding the functional impact of CNAs in tumor development.

Functional implications of unclassified variants in BRCA1/BRCA2, fine-mapping of risk-associated variants (from GWAS) and understanding the functional impact of the more common SNPs such as TOX3 and the role of FOXA1 remain to be determined.

Tackling these questions, using combinations of genomic engineering, genome-wide approaches as well as single-cell and live imaging approaches, with the ultimate aim of understanding the functional impact of chromatin architecture, represents an exciting challenge.

As understanding of the functional impact of ANK3 on cognition is currently limited we also undertook a hypothesis generating analyses on the effect of allelic variation in ANK3 on other aspects of cognition.

A more detailed understanding of the functional impact of TJs in gastric cancer, however, is still missing.

Ultimately, only a knowledge of the epigenomes of individual cell types will enable a full understanding of the functional impact of chromatin-level regulation on genome activity.

Understanding the functional role of ECM molecules in toxic liver injury could have important therapeutic implications and considerable impact on hepatic bioengineering applications and in vitro modeling of xenobiotic metabolism.

This might represent a further step in understanding the functional neuroanatomy of the trigeminal pathway.

Such a combined approach will facilitate the understanding of the functional impacts of genetic and epigenetic variations on transcription and molecular mechanisms involved in allergic diseases.

From a management perspective, this study showed that the combination of gene expression and admixture analyses greatly contributes to our understanding of the functional impacts of introgressive hybridization following the introduction of domestic individuals in wild populations.

Characterization of the genetic architecture of gene regulation in the human colon informs the functional impact of GWAS variants and could benefit understanding of the biological differences in colonic disease between different ethnic groups.