Understanding the basic principles that govern RNA binding by aminoglycosides is important for the design of new generations of antibiotics that do not suffer from the known mechanisms of drug resistance.
Early models tended to be oriented towards "understanding the basic constraints that govern human analogical thinking" (Hummel and Holyoak 1997: 458).
Therefore, understanding the basic mechanisms that lead to aneuploidy in ovarian cancer is crucial in determining the appropriate course of treatment.
It's hard to read without understanding the basics, a fact that D-Wave engineers factored for in offering online documentation.
"We don't have the legacy of hundreds of years of understanding the basics and the natural history that other specialties do," Fox says.
In a recent interview in Politico, he referred to Emirates' recent routes from the U.S., noting: "these can't be routes that a normal for-profit airline would ever be able to economically operate," adding, "after 20-some years of being in this business and understanding the basics of economics, you knew that the economics on routes like JFK-Milan, without subsidies, wouldn't work".
That requires understanding the basics of albedo -- which to put it simply is the amount of solar energy reflected off a surface.
The Yale group proceeds from the premise that understanding the basic biology of the melanocyte will lead to tailored treatment that addresses pathways of malignant transformation.
These examples illustrate that understanding the basic principles of chromatin biology is of immediate relevance for a variety of human diseases.
A recent empirical breakthrough in understanding the basic nature of homeopathic remedies demonstrated that even commercial metal remedies (source materials: gold, copper, tin, zinc, silver, and platinum) triturated, diluted and hand-succussed to 30C or 200C potencies (both above Avogadro's number) retain nanoparticles of their source material [ 2].
