Sentence examples for understanding of vinculin function from inspiring English sources

Advances in technology will enable us to achieve a clearer understanding of vinculin function.

The phenotype of cells expressing vinculin-ΔEx20 reflects vinculin interactions in adhesion sites independent of auto-inhibition and cytoskeletal coupling, and contributes to a better understanding of vinculin functional regulation in cells and tissues.

The constitutively active behavior of the protein is associated with severe malformations during embryonic development in mice providing in vivo evidence for the functional importance of a fine tuned regulation of vinculin function.

The significance of vinculin function in tissue organization and mechanical stability of the heart muscle was demonstrated in heterozygous animals with one vinculin null allele and through heart-specific vinculin knock-out, which leads to cardiomyopathies and/or ventricular tachycardia causing sudden death of young mice [15], [16].

Understanding of LTR structure increases understanding of LTR function, and of functional genomics.

To address the influence of vinculin-ΔEx20 on vinculin function in homozygous VCL-ΔIn20/21 VCL-ΔIn20/21mary Membryosm E10.5 embryos were cultured.

Our understanding of its function will increase significantly," she notes.

Understanding the diversity of these alleles can contribute to our understanding of Hd1 function.

Still, no molecular understanding of protein function is currently available.

The understanding of their evolution is of critical importance for the understanding of their function.

Its presence in a transgenic animal reveals the potential of splice variants in the vinculin gene to alter vinculin function in vivo.