Sentence examples for understanding of the pathway from inspiring English sources
Overall, our results enrich the understanding of the pathway with interactions and provide structural details for the human apoptosis pathway.
The pharmacological manipulation of the sphingolipid metabolism in cancer therapeutics necessitates the detailed understanding of the pathway.
Despite having identified multiple membrane trafficking regulator proteins implicated in the removal of MHC-I from the cell surface, it remains unknown what cellular compartments are used by Nef during this process precluding our understanding of the pathway subverted by HIV-1 to evade immune surveillance.
A mechanistic understanding of the pathway from soluble, native protein to insoluble amyloid is crucial for therapeutic design, and recent efforts have helped to elucidate the key molecular events that trigger protein misfolding.
In particular, a full understanding of the pathway should lead to the ability to direct synthesis of a large number of novel cyclic peptides based on the Amanita toxin scaffold by genetic engineering of the encoding genes.
In the last 5 years, there has been an impressive amount of drug development that has resulted in better understanding of the pathway.
Therefore, an enhanced understanding of the pathways that contribute to β-cell failure is imperative.
Underlying mechanisms are still under debate and better understanding of the pathways involved may contribute to more targeted treatment strategies.
Further understanding of the pathways, mechanisms and consequences of M. tuberculosis dissemination could have a major impact in designing novel vaccines and therapeutic strategies.
Improved understanding of the pathways and influences that control aquatic-to-terrestrial contaminant transport will be critical for effective risk management and remediation.
Several important advances have been made in our understanding of the pathways that lead to cell dysfunction and death in Parkinson's disease and Huntington's disease.
