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Future investigations to determine the precise mechanism by which LOV1 acts in two intersecting pathways will provide a better understanding of the modulation of reproductive development in plants under continuously changing temperature conditions.
The target site-specific actions of SERMs are not well understood, but there is an emerging understanding of the modulation of the SERM ER complex in breast cancer.
Further studies on the role of DELLA proteins during virus infections will add to the understanding of the modulation of SA signaling by Tobamovirus.
A more detailed understanding of the modulation of CD47 could open new avenues for CSC-based immunotherapy for treating gastric cancer.
The related discovery of the kisspeptin-neurokinin B-dynorphin (KNDy) pathway in the last decade has further strengthened our understanding of the modulation of GnRH secretion by endocrine, metabolic and environmental inputs.
Computational modeling and mouse adoptive transfer studies were combined to gain a better mechanistic understanding of the modulation of CD4+ T cell differentiation and plasticity at the intestinal mucosa of mice.
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Identifying the phenotype of spinal cells expressing the various DA receptors is critical for better understanding of the DA modulation of the spinal cord functions.
Our findings are important because they provide, for the first time, a structural understanding of the allosteric modulation elicited by mecamylamine enantiomers at each hα4β2 stoichiometry.
These findings are valuable for the understanding of the allosteric modulation elicited by each enantiomer, and this basic knowledge could be beneficial for the development of novel therapies for the treatment of several neurological disorders involving α4β2 AChRs.
Our research not only presents a deep understanding of the optical-electrical modulation mechanism but also paves the way for their future applications.
This add-on can be an effective tool to give students better understanding of the space vector modulation algorithm for different control tasks in power electronics area, and can motivate them for learning.
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