Sentence examples for understanding of the clock from inspiring English sources

The Neurospora model has elucidated our fundamental understanding of the clock as nested positive and negative feedback loop, regulated by transcriptional and posttranscriptional processes.

Much of our understanding of the clock mechanism comes from the identification of specific mutations that affect circadian behavior.

These results reveal the neuroanatomical basis PDF's various circadian functions and refine our understanding of the clock neuron circuitry of Drosophila.

Identification of clock components has been central to our understanding of the clock mechanisms.

Our understanding of the clock mechanism has been facilitated by the relatively simple nature of the circuits that control circadian rhythms in both vertebrates and invertebrates.

In order to expand our understanding of the clock function in biotic and abiotic interactions, we identified three core clock components (LHY, TOC1, and ZTL) in a wild tobacco, Nicotiana attenuata, which has been developed as a model system for understanding ecological performance in native habitats, in particular the Great Basin desert in Utah.

An understanding of how the clock influences expression of the drug target or elements of the drug's metabolic pathway can be utilised to optimise dosing times to make treatment more effective; this might maximise effectiveness and minimise side effects.

A greater understanding of how the clock couples to the immune system, and the involvement of clock outputs in disease pathogenesis, is likely to produce novel therapeutic targets for the treatment of not only RA but also other inflammatory disorders.

These approaches will provide a deeper understanding of the biological clock, and of clinical problems associated with it, such as sleep disorders.

Work over the past 15 years has led to an amazing increase in our understanding of the circadian clock, light input and jet lag, says Stuart Peirson of the Nuffield Laboratory of Ophthalmology at Oxford University.

We agree with the reviewer and we have revised the manuscript to highlight how our findings fundamentally alter our understanding of the plant clock.