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Research of a past decade and a half leaves no doubt that complete understanding of protein functionality requires close consideration of the fact that many functional proteins do not have well-folded structures.
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By carefully investigating recovered clusters, we may have a better understanding of protein functionalities, cellular organization, as well as the underlying signal transduction mechanisms for deriving future systematic intervention strategies.
The detection of a protein domain has been shown to be suggestive of protein functionality [ 32].
However, although such in vitro experiments are now being successfully applied to identify the minimal components and interactions of protein networks, we are still far from understanding the mutual interdependence of protein functionalities and physical parameters in generating nonhomogeneous protein distributions for providing positional information within the cellular compartment.
A crucial challenge of the proteome era is to use the genome information for a better understanding of protein expression, protein cellular distribution and functionality discovery not only in normal but also in pathological processes [ 1, 2].
Protein design tests our understanding of protein stability and structure.
Similarly, the crystallization of H. volcanii XAD could open new routes for optimization of this protein functionality through protein engineering.
The significance of this class of editing on protein functionality is self-evident.
How Syt I mediates this cellular event has been a question of extensive study for decades and yet, a clear understanding of the protein's diverse functionality has remained elusive.
Intronless genes are a characteristic feature of prokaryotes and an important resource for understanding the rules of gene structure and organization, protein functionality and evolutionary differences between eukaryotes and prokaryotes.
The impact of the mutation on protein functionality may affect the severity of the symptoms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com