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These findings advance our understanding of neurotrophic function of brain sex steroids.
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The results of our study may extend the knowledge of the neurotrophic function of pSap, which should be considered essential for the survival and maintenance of human cortical neurons.
Understanding of LTR structure increases understanding of LTR function, and of functional genomics.
In addition, the neurotrophic function of PEDF promotes the survival of retinal neurons [ 98, 99], retinal progenitor cells [ 80], RPE cells [ 100] and photoreceptors [ 98, 100– 100].
Hence, the high energy demands imposed by neuronal function are not supported by the age-declining neurotrophic function of astrocytes; challenges to this neurotrophic support – in terms of astrocyte-generated lactate – become exacerbated with the age-dependent reduction in expression and translocation to the plasma membrane of neuronal glucose transporters (GLUT3 and GLUT4) (Jiang et al., 2013).
This neurotrophic function of TBPH, nevertheless, was not sufficient to rescue the neuronal levels of the vesicular protein Syx.
Therefore, studies measuring neurotrophic function of serum VEGF levels in AD patients should evaluate depressive symptoms to minimize the effect of the possible coexistence of both diseases.
Our understanding of its function will increase significantly," she notes.
Understanding the diversity of these alleles can contribute to our understanding of Hd1 function.
Still, no molecular understanding of protein function is currently available.
The understanding of their evolution is of critical importance for the understanding of their function.
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