Sentence examples for understanding of molecular pathways from inspiring English sources
Several in vitro and in vivo studies have contributed to our understanding of molecular pathways involved in disease development and their critical interplay, leading to the identification of potential treatment targets.
The differential transcriptome analysis provides better understanding of molecular pathways leading to cancer, which in turn allows designing the effective strategies for diagnosis, therapeutic intervention and prediction of therapeutic outcome.
A better understanding of molecular pathways and differentiation factors, those that play a key role in transdifferentiation are of extreme importance in designing novel strategies for the treatment of obesity and associated metabolic disorders.
Thus, a clear and in-depth understanding of molecular pathways leading to modulation of autophagic intermediates through transcription, microRNA modulation, and protein protein interactions would lead to potentially beneficial adjustments of existing chemotherapeutics supplemented with small molecule- or microRNA-based regimens.
A comprehensive understanding of molecular pathways underlying GBM behavior would enable the development of targeted therapeutic approaches.
To gain a more comprehensive and system-wide understanding of molecular pathways in GBM, more sensitive gene expression profiling technology is needed.
To progress in the understanding of molecular pathway(s) underlying the advent of the disease, gene-expression profiling of WM cells has been previously performed; revealing a homogeneous expression profile, more similar to that of CLL than that of MM.
Small molecules have proved to be powerful tools for understanding the importance of molecular pathways in development and disease.
Recent advances in understanding aberrant signaling of molecular pathways in melanoma provide the bases for the current development of novel therapies for this cancer.
As recent advances have been made in our understanding of the molecular pathways of HCC, the metastatic potential of early HCC has been confirmed by gene expression assessment using microarray analysis [ 9].
Thus, there is a need for an improved understanding of the molecular pathways of ovarian carcinogenesis.
