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So a better understanding of modulation of this cleavage event and the mechanism for the truncated PrP fragments as mediators of a toxic cellular response may be very important in dissecting prion disease pathogenesis.
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Implications of these observations for our understanding of different modulation processes in the inner three-dimensional heliosphere are presented.
Although growth plate response to mechanical stress has been increasingly studied, our understanding of mechanical modulation of neonatal growth plate is incomplete, especially concerning biochemical changes.
The emerging understanding of selective modulation of Gamma Amino Butyric Acid (GABA) receptors allows an increase in the development of clinically efficacious and subtype selective drugs for these targets [1].
Future investigations to determine the precise mechanism by which LOV1 acts in two intersecting pathways will provide a better understanding of the modulation of reproductive development in plants under continuously changing temperature conditions.
While the model is deliberately minimal, it does reflect two of the most important mechanisms that have previously been shown to be relevant for the understanding of SOD modulation [35] [37], [50].
Moreover, a steady flow of new neuroimaging studies will continue to increase our understanding of dopaminergic modulation of human behavior.
These emerging studies advanced the understanding of membrane modulation processes that are mediated by membrane proteins.
The target site-specific actions of SERMs are not well understood, but there is an emerging understanding of the modulation of the SERM ER complex in breast cancer.
Further studies on the role of DELLA proteins during virus infections will add to the understanding of the modulation of SA signaling by Tobamovirus.
A more detailed understanding of the modulation of CD47 could open new avenues for CSC-based immunotherapy for treating gastric cancer.
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