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The important role in hepatocellular carcinoma tells us that understanding of miRNA function will provide us with broad prospects to understand and overcome tumor in the future.
A systematic overview over miRNA regulome can contribute to more targeted study design and understanding of miRNA function.
It therefore appears that progress in our understanding of miRNA function has been limited by the difficulty in accurate target prediction and validation.
This work addresses the latter goal, with an emphasis on invertebrate genetic models that are likely to have a major impact on advancing understanding of miRNA function.
These miRNAs add to the growing database of new miRNA and lay the foundation for further understanding of miRNA function in the regulation of Porphyra yezoensis development.
Our current understanding of miRNA function is inferred largely from studies of the effects of miRNAs on steady-state mRNA levels and from seed match conservation and context in putative targets.
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As such, a complete understanding of miRNA functions and their precise regulatory mechanisms remain elusive.
These findings reveal important information about the regulation mechanism of miRNAs in P. trichocarpa and promote the understanding of miRNA functions during the drought response.
These findings reveal important information about the regulatory mechanism of miRNAs in C. sinensis, and promote the understanding of miRNA functions during the cold response.
Our study provides more information about the regulatory network of miRNAs in soybean and advances our understanding of miRNA functions during seed development.
> -wrap-foot> In order to resolve the limitation of MRMs and gain understanding of miRNA functions in specific biological processes, the concept of FMRMs [ 85] was proposed.
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