These aspects render the molecular and biologic characterization of SARS-CoV important not only for understanding the determinants of its pathogenic potential but also for planning rational strategies of antiviral therapy and vaccination.
Genome sequencing of the pathogen will make more contribution to the understanding of its evolutionary relationship with other pathogenic fungi, and efficiently screening of pathogenicity-associated genes as well as detection of its virulence variation under its interaction with host.
Abdominal aortic aneurysm thus represents an accessible spatiotemporal model of human atherothrombotic progression towards clinical events, the study of which should allow further understanding of its pathogenesis and the translation of pathogenic biological activities into diagnostic and therapeutic applications.
Mycobacterium canettii is the mycobacterial species most closely related to M. tuberculosis complex (Brosch et al. 2002), and a better understanding of its evolution would also contribute to our understanding of the emergence of human-pathogenic mycobacteria.
Given the wide-ranging effects of periodontal disease, an understanding of the pathogenic mechanisms that underlie it is crucially important.
Results from this study provide an advanced database that may help in deciphering the genetics of AD and serves as a potential model to promote a better understanding of the pathogenic interplay between Al accumulation, Aβ aggregation, and its neurotoxicity.
This study should contribute to an understanding of the pathogenic mechanisms by which P. multocida and other pathogens in thePasteurellaceae family cause disease and identify novel live vaccine candidates and new potential antibiotic targets.
Thus a comprehensive understanding of the pathogenic mechanism of the development of NAFLD is extremely important (Cohen et al., 2011).
Thus, finding appropriate proteostasis regulators implies a profound understanding of the pathogenic mechanisms operating within each peculiar cellular context.
Clearly, bipolar disorders deserve a higher priority in the research agenda to gain understanding of underlying pathogenic mechanisms, reduce the diagnostic delay, and improve treatment strategies.
