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Better understanding of inflammatory processes might help tailor such therapies more effectively and improve their efficacy.
Although both Pirc and KAD rat models show enhanced susceptibility to agents that induce inflammation, the two models contribute in different ways to our understanding of inflammatory processes and their effect on colon cancer risk and progression.
The different functions of the HIF α isoforms in the regulation of IL-8 may add to our understanding of inflammatory processes, hypoxic response, and further blood vessel formation.
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Taken together, these data open new perspectives for studies aimed at a better understanding of the response of inflammatory processes to physical exercise.
Although research has made tremendous advances in our understanding of the mechanisms leading to initial brain injury, damage progression and the implication of inflammatory processes in damage evolution, there are still no widely applicable treatments [2,3].
Specific imaging of inflammatory processes is a demanding task.
Nevertheless, a better understanding of the inflammatory processes will be needed before these applications become clinical utilities.
Ultimately, our understanding of the inflammatory processes that protect versus those that contribute to neuronal damage will be a prerequisite to designing effective new therapies for diseases affecting the nervous system.
Animal models have enhanced our understanding of the inflammatory processes that take place in the intestine following chemotherapy [12] [14], and in the clinical setting of SCT the relationship between intestinal damage and the inflammatory response has become better appreciated [4], [15].
Therapy is aimed at restricting inflammation and classically includes non-steroidal anti-inflammatory drugs or steroids such as methotrexate, which may result in serious side effects, although a new generation of biological therapies has been developed recently as a consequence of our better understanding of the inflammatory process in health and disease.
A better understanding of the inflammatory process in the dystrophic muscle and of the mediators involved might open alternative therapeutic perspectives.
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CEO of Professional Science Editing for Scientists @ prosciediting.com