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At the same time further examination of cellular TT jSR domain variability and analysis of different cardiac regions will contribute to a more realistic understanding of heart function.
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Studies of heart function after longer term anabolic steroid use found damage, weakening and an increased risk of heart failure.
ECMO maintains tissue oxygenation pending recovery of heart function.
Understanding the details of these complex systems, as well as the interactions among them, is crucial for understanding heart function in health and disease.
Knowledge of myocardial fiber architecture is essential towards understanding heart functions.
"It opened a whole new era for understanding how the heart functions as a pump and what goes wrong when it fails to pump efficiently," said Dr. Heinrich Taegtmeyer, a professor of medicine at the University of Texas Health Science Center in Houston.
For providing a framework for understanding normal and abnormal heart function, "Ed Sonnenblick occupies an honored place in the pantheon of the greatest heart and blood vessel physiologists of the 20th century," said Dr. Braunwald, who worked with Dr. Sonnenblick at Harvard and at the heart institute.
Many patients reported low levels of understanding concerning their symptoms and heart function deterioration.
Understanding of LTR structure increases understanding of LTR function, and of functional genomics.
And finally, although opportunities may begin in rare Mendelian conditions like sarcomeric cardiomyopathies, the insights gained are likely to also advance understanding of cardiac function relevant to more common forms of heart failure.
In the last 70 years, scientists have developed an understanding of lipoprotein function, often in relationship to lipid transport and heart disease.
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