New therapeutic approaches are currently evolving from the combination of tissue-engineering strategies with the better understanding of cellular interactions and mechanisms determining stem cell differentiation.
The four later studies are particularly interesting in cellular biology since they concern the specific forces associated with cell adhesion proteins, thereby contributing to refine our understanding of cellular interactions.
Functional analyses of growth factor receptor-ligand interactions have been informative in the understanding of cellular interactions and signalling molecules important for both early hematopoietic development and regulation of stem and progenitor cells.
Along with these discoveries and their potentials, there are technologies that are useful in culturing cells, preserving tissues, and improving our understanding of cellular interaction, which now provide a basis for tissue engineering.
This example demonstrated the ability of programming microbial consortia via rational design of cellular interactions by rewiring cellular communication systems, providing novel insights in understanding and programming microbial community patterns that orchestrate the complex coexistence of living systems.
Significant advances have been made in recent years that have contributed to our understanding of the cellular interactions in the RA joint involving macrophages, T and B lymphocytes, and synovial fibroblasts.
In RA, in which significant advances have been achieved in our understanding of the cellular interactions in the RA joint involving macrophages, T and B lymphocytes, and synovial fibroblasts, there is still a need for therapeutic strategies that prevent the extensive cartilage and bone loss, despite the clinical success of anti-TNF therapy for RA.
Understanding the cellular interactions that lead to the control of monocyte/macrophage (Mo/Ma) activation is, therefore, of fundamental importance to the field of tumor immunology.
Understanding the cellular interactions that promote the help effect is essential to being able to manipulate peripheral reconstitution.
Ongoing studies of the pathogenesis of systemic sclerosis (SSc) have yielded improved understanding of the complex cellular interactions that occur in this heterogeneous connective tissue disease.
Though in vitro tissue engineering has greatly increased our understanding of cellular behavior and cell-material interactions, this methodology is often unable to recreate tissue with the hierarchical organization and vascularization found within native tissues.
