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Achieving this understanding necessitated moving away from β3-KO animals, which are often criticised for sustaining angiogenesis through developmental upregulation of VEGFR2, to a more subtle, albeit global, alteration in β3-integrin expression – β3 heterozygosity.
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To deepen our understanding necessitates taking more sophisticated instrumentation to harder-to-reach places.
Such understanding necessitates a description of the raw observations, and a delineation of computational models and mathematical theories that accurately capture fundamental principles behind the observations.
The PSTs became aware of how student and teacher discourse is interrelated, with Student F critiquing his own Orienting strategies that led to insufficient student understanding, necessitating his intervention in the dialogue.
How has an understanding of transnationality necessitated a reconceptualization of the way we traditionally think about the nation-state and citizenship?
These studies mostly presented cartoons and short narratives that necessitated understanding the beliefs of the acting characters.
Understanding this variation necessitates a fundamental understanding of the evolutionary drivers of leaf emergence across temperate forests.
Anna Hook, senior policy adviser with Essex council, said her authority's journey from service provider to "strategic commissioning organisation" necessitated greater understanding of the risks faced by charities.
In particular, the high dynamic loading experienced by machine parts necessitates understanding fatigue properties in life limiting components.
Understanding neurite outgrowth necessitates quantitative determination of the role of molecular gradients on growth cone navigation under dynamic physiological conditions.
The layered material architecture, however, leads to a complex delamination failure within the pultruded material, thus necessitating understanding of the progressive failure mechanism of such joints under axial tensile loading.
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