Sentence examples for understanding mutations from inspiring English sources

Background: Identification of human cytomegalovirus (CMV) genome variation is important for understanding mutations associated with drug resistance.

Structures of membrane metalloproteases provide the basis for understanding mutations associated with premature aging.

With this information, by understanding mutations, treatment can begin with the individual in mind.

mCSM outperforms other methods, demonstrating its applicability to understanding mutations that lead to disease.

In maize, the P2 nuclear genotype is used as a system for understanding mutations in mtDNA, where abnormal recombination products remarkably increase as the copy number of subgenomic molecules of maize mtDNA increases [ 36].

Based on current understanding, mutations in SMAD3 are absent in almost all cancer types while mutations of SMAD4 are frequent in pancreatic and colorectal cancers but rare in breast cancer.

Finally, information from the Homeodomain Resource has been used as a reference to aid in understanding mutation data from patients with disorders such as idiopathic short stature and Leri-Weill dyschondrosteosis (20) and brachydactyly types D and E (21).

It meant we could get on with understanding how mutations in it led to breast cancer.

Porta-Pardo, E., Hrabe, T. & Godzik, A. Cancer3D: understanding cancer mutations through protein structures.

Basic research studies, including the characterization of genetically engineered mice, provide a mechanistic framework for understanding how mutations create the clinical characteristics observed in patients.

Our structures, along with mutagenesis and kinetic studies, provide a molecular basis for understanding pathogenic mutations and catalysis, as well as a template for structure-based drug design.