Finding the common substructures shared by two proteins is considered as one of the central issues in computational biology because of its usefulness in understanding the structure-function relationship and application in drug and vaccine design.
So far, progress in understanding the structure-function relationships of membranes and understanding of the lipid-drug interaction appears to be of crucial importance in understanding the mechanisms involved in cellular drug accumulation.
Furthermore, this study also describes the influence of several mutations on the enzymatic activity of LinB and helps in understanding the structure-function relationship.
We attempted to model the structure by homology modeling using the bioinformatics program (PS) to obtain an in-depth understanding of the structure-function relationship of the C-terminal domains of these SSBs [ 70, 71].
The identification of pharmacological sites helps in (1) understanding the structure-function relationships of PLA2 enzymes, (2) developing strategies to neutralize the toxicity and pharmacological effects by targeting these sites, and (3) developing prototypes of novel research tools and pharmaceutical drugs [ 7, 8].
Therefore, the positively selected site may play an important functional role and could represent an interesting target site for future mutagenesis experiment thus facilitating our understanding of the structure-function relationships in FoxO genes.
Therefore, this positively selected site may play an important functional role and could represent an interesting target site for future mutagenesis experiment thus facilitating our understanding of the structure-function relationships in UCP genes.
Therefore, our method may complement these other analysis as well as to guide experimentalists to direct experiments to complete our understanding about the structure-function relationship present in metabolism.
The disulfide connectivity established here would help further in understanding the structure – function relationship in MtbDGC.
However, little effort has been made so far in understanding the structure, function, and conversation of transcriptional networks in non-model organisms, e.g. corals, despite their ecological importance.
