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Whenever possible, coupling epidemiological research and/or qualitative field studies, provides valuable elements for the further understanding and extrapolation of actions and impact.
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This includes ex-post and ex-ante evaluation, a better understanding of extrapolation of historical trends and the transferability of research results.
This review considers current literature evidence to guide development of bespoke paediatric biopharmaceutics tools and reviews current understanding surrounding extrapolation of adult methodology into a paediatric population.
This allows better understanding of PK properties, more rational candidate selection, and extrapolation of dose levels, of routes of administration, and of data across species.
My work is about evolution and extrapolation.
3. Use interpolation and extrapolation to make predictions from select data sets.
Veracity does not make excellent stage work; imagination and extrapolation do.
Specifically, it is used for: extrapolation across species, extrapolation across dosing scenarios, and extrapolation across routes of exposure.
We consider interpolation and extrapolation designs with controlled bias.
It is difficult, based on the information provided in the study, to determine how the authors handled key assumptions such as extrapolation rates and extrapolation from the survey sample to the broader population.
Details on the study catchment and extrapolation factors.
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