Following the understandable proprietary route, Gilead, the developer of TAF, has been developing it in the context of a second-generation "quad" pill, combining TAF with 3 of its own compounds: the integrase inhibitor elvitegravir, emtricitabine, and a pharmacokinetic "booster," cobicistat, which has no anti-HIV activity but is needed to increase elvitegravir levels.
It is understandable that the routes in narrow straits such as the Malacca strait are difficult to be drawn with the correct directions.
But in a city like New York, the two-roof route has understandable appeal, especially for couples with an escape hatch, a k a a summer house, and no children.
Their increasing, understandable anxiety for a route back into the game, however, left the Portuguese league leaders vulnerable to a Liverpool break and they survived several scares before Torres delivered the cushion of a third.
Given that they could see no reason to believe the mainstream care system will ever deliver the personalised service that political and sector leaders have promised, this is entirely understandable and the only route to enable this group of people to continue to enjoy a reasonable quality of life.
It's understandable why it went this route, but it doesn't lend itself well to meeting someone special – unless you're open to meeting people anywhere (which some are), or are fine with just making new friends and seeing where that leads.
While Ken Rosenthal writes on Foxsports.com that Riggleman's frustrations are understandable, he still chose the wrong route.
Struggling with depression can be debilitating to athletic performance, and repeated taunting serves to exacerbate the condition, so it is understandable that Martin felt that his only viable route was to leave the team.
Given how difficult it is to get a hold of the H1N1 vaccination, it is understandable that frustrated consumers might be drawn to alternative routes.
