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Understanding the mechanisms which drove the evolution of such a large family would help understand the specificity of each GPCR sub-family with applications to drug design.
Further experiments are required to understand the specificity of the results regarding polarity and region used for stimulation.
The last section discusses the results and concludes about their usefulness to further understand the specificity of current port and maritime transport challenges.
We focus on a class of models where the activity is linear to understand the specificity of several learning rules (Hebbian, trace or anti-symmetric learning).
Experimental, theoretical, and molecular dynamics studies were performed to show the fundamental mechanism behind layer formation in the composites and to understand the specificity of preferential polymer-CNT interactions.
In doing so, the open part of the question is kept to a minimum and the input from the SPOCs will be very targeted and contain exactly what is needed to understand the specificity of their system.
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Women wanting to escape violence at home and rebuild their lives thereafter are more likely to do so if they have an organisation that, as Gabriela Quevedo of LAWA puts it, "understands the specificity of their background".
Numerous studies to understand the specificity difference of σ70 and σ38 have revealed only some clues to explain the divergent functions of these rather homologous sigma factors [51], [52], [53], [54], [55], [56], [57].
Docking simulations can be used to understand the specificity and selectivity of ligands as well as guide in the identification and design of inhibitors.
While this model must be considered to be a low-resolution approximation of the ERK2Ets complex, it is nevertheless of significant value, because it provides an important framework from which to begin to understand the specificity and mechanism of ERK2 towards Ets-1 and potentially towards other substrates also.
These analyses also demonstrate the need to better identify and understand the specificity and expression of gene families and/or different transcripts from a single gene in post-harvest processes.
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