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This could be extremely valuable in ARDS to understand the pathological changes that occur during the development and recovery stages of this disease when lung specific biospecimens can be challenging to collect.
The present study provides new biological basis to understand the pathological changes and proteomic differences of TB syndromes.
A key reason to build integrated molecular network models is to understand the pathological changes at a molecular level between normal and ILD states.
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The ability to longitudinally assess GM changes in MCI offers new perspectives to better understand the pathological processes underlying AD and to monitor the effects of treatment on brain structure.
Further work is needed to understand the pathological basis of these findings.
To understand the pathological meaning of autophagy, we tested its regulatory effect in RASF.
Thus, one current major problem is the overlapping neuropathology and the as yet incompletely understood molecular constituents of the pathological changes.
Although in this last group of diseases, also referred to as tauopathies, patients are often distinguishable upon pathology, patients with less typical or mixed pathology are difficult to classify, demonstrating the need to understand the underlying processes behind the pathological changes.
Therefore, further studies of Wnt signaling, and particularly dysfunctional Wnt signaling in AD, are needed to fully understand the biological mechanisms that underlie the pathological changes in AD.
The pathological changes due to AD can precede cognitive symptoms by decades2.
Those results were suggestive, but still did not prove that YKL-40 caused any of the pathological changes of asthma.
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