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The systematic characterization of the interactive domains is necessary to understand the functional importance of sHSPs in assembly of cytoskeletal proteins.
To understand the functional importance of NPM in the nucleolus, endogenous NPM was specifically depleted by RNAi in HeLa cells.
In this work, subnetworks of different sizes were identified and analyzed across the stages to understand the functional importance of the Significant DNA methylated genes.
The correct assessment of the individual allelic diversity pattern and the underlying structural sequence variation is the basic requirement to understand the functional importance of MHC variability [ 5].
To understand the functional importance of the interactions between ARF6, BZR1, and PIF4, we analyzed the effects of genetic alteration of each component on the growth responses to changes in the other activities.
We firmly believe that the answers to these questions hinge on our ability to fully understand the functional importance of each microcephaly protein and build upon the existing protein interaction network.
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A genome-wide analysis of chicken snoRNAs is therefore of great importance to further understand the functional evolution of snoRNAs in vertebrates.
Due to the importance of microbial and host derived metabolites for intestinal health, it is important to better understand the functional consequences of microbial dysbiosis.
Given the appropriate antibodies, this Ion Torrent MeDIP-Seq approach potentially offers a means to study the functional importance of other poorly understood DNA modification variants such as 5-formylcytosine and 5-carboxycytosine.
The functional importance of this shift could be better understood with further studies on c-Cbl-mediated HER2 subcellular trafficking and the function of K63-linked HER2 ubiquitination.
The functional importance of colostral leukocytes is not yet fully understood.
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