Sentence examples for understand the functional changes from inspiring English sources

These findings are valuable in helping us understand the functional changes which underlie clinical symptoms associated with SAD; however, the extrapolation of any potential biomarkers and the clinical translation of the results have been hindered by the group level inference of the data.

The Seahorse XF analyzer was used to evaluate mitochondrial respiration in isolated synaptic mitochondria to understand the functional mitochondrial changes that are associated with our observed OXPHOS proteomic changes.

Experimental systems where major reorganization of nuclear architecture can be induced under defined conditions, may help to better understand the functional implications of such changes.

Further we attempted to understand the functional relevance of methylation changes by investigating whether the differentially methylated CpG sites in VEGF, FLT-1 and KDR gene promoters were located within transcription factor binding sites.

Interaction networks are very useful to better understand the functional significance of gene expression changes.

There is thus a pressing need to understand the functional genome; that is, the changes defined by regulatory mechanisms overlaying the genetic structure.

To understand the functional implications of oxLDL-mediated changes in p-JNK, p-IRS-1, and p-AKT, we examined the effect of oxLDL on physiologic correlates of insulin sensitivity in 3T3L1 adipocytes.

To understand the functional implications that these gene expression changes may have, they were classified by function (Fig. 1C, S2).

To understand the functional impact of those gene-expression changes better, we have to be able to match the naturally occurring dynamics as closely as possible," says Silvana Konermann, an MIT graduate student in brain and cognitive sciences.

In order to understand the functional significance of the-357 T/C change, we used a reporter assay with luciferase.

As shown in this study, structure-based analysis of specific mutations that alter the binding and function with defined chemical changes is needed to understand the functional mechanism of protein-protein interactions between IL-3 and its receptor.