Sentence examples for understand the cellular pathways from inspiring English sources
In light of the significance microglia may hold as therapeutic targets directed against Alzheimer's disease, it becomes vital to understand the cellular pathways that maintain microglia survival during Aβ toxicity.
We next wanted to understand the cellular pathway in which BICDR-1 is involved.
To better understand the cellular processes and signalling pathways involved in conidial germination, the EST sequences of all 1561 genes were matched to GO terms at the Saccharomyces Genome Database (for detailed results, see Additional file 2).
The uncovering of potential pathways across genes helps biologists understand the cellular functions of each gene and protein.
In order to better understand the cellular roles of ascorbate, we have examined the distribution of the three major pathways of ascorbate biosynthesis in eukaryotes.
To fully understand the cellular response to ionizing radiation, it is necessary to have a comprehensive picture of the normal expression of genes and different signaling pathways involved in each specific tissue.
Understanding the effect of increasing levels of ROS on the differential expression of sperm proteins is important to understand the cellular processes and or/pathways that may be implicated in male infertility.
We next sought to understand which of the cellular pathways are disturbed in the U6atac −/− larvae as this would also help to identify those U12-type genes that are primarily responsible of larval lethality.
We study telomerase both in vitro, to understand its unique structure and dynamic nucleic acid handling, and in vivo, to understand the complex cellular pathways for active RNP biogenesis and regulation of telomerase action at telomeres.
However, to exploit these alterations, it is necessary to understand how they influence the cellular pathways that control the sensitivity or, conversely, resistance to chemotherapeutic agents.
In addition, many drug candidates failed clinical phases because the mechanisms of the cellular pathways they target are incompletely understood.
