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Recent advances in our understanding of the mechanisms regulating macroH2A1 alternative splicing [ 18, 35] are not helpful to understand in response to which stimuli the protein levels of the isoforms change in the liver.
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The function of p53 is best understood in response to genotoxic stress, but increasing evidence suggests that p53 also plays a key role in the regulation of metabolic homeostasis.
Third, we analyzed c-peptide levels over two consecutive days in the same laboratory using the same platform to understand changes in response to intervention.
If a student detects all of the correct answers and omits all of the incorrect answers of an item, the student can be expected to understand movement in response to forces in the particular problem context provided by the item.
This study generates important baseline data for ongoing efforts to understand differences in response to Bd between susceptible and resistant frog species and the effects of chytridiomycosis in natural populations.
As illustrated in Figure 1, it is now understood that in response to apoptotic stimuli such as NGF deprivation, neonatal sympathetic neurons activate the intrinsic mitochondrial pathway of apoptosis.
The basis for this difference in not understood but might be exploited in the future to understand signal transduction in response to OLFM1.
Two species of chipmunks have become the focus of efforts to understand interspecific differences in response to climate change in Yosemite National Park.
In order to measure the effects of premium subsidies, it is necessary to understand insurance demand in response to subsidy rate as well as insurance coverage and premium rate changes.
Typically, the discovery metabolomics is addressed to identify biomarkers to improve early diagnosis, accurate prognosis and aid adequate monitoring of disease and understand physiological changes in response to environmental alteration (Gibbons et al, 2015).
It is critical to properly understand the metabolism in response to culture environment, where the systems biology approaches including metabolite profiling [65] and integration of different levels of information such as metabolites, fluxes, transcript, and protein abundance [66] are useful.
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