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It may thus be essential for optimal patient care to understand functioning from a bio-psycho-social perspective, which is currently best represented in the framework and model of the WHO International Classification of Functioning, Disability and Health ICFF).
However, having a universally accepted framework to understand functioning is challenging due to the contextual nature of the concept, which brings a serious problem to the use of exiting cross-cultural measures of functioning in LAMICs.
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Functional genomics attempts to understand function at the broadest level (the genomic level).
These studies provide the basis for a physical or a mathematical model that may help understand function.
To understand function requires demonstration of whether the kinase and ROC (GTPase) domains are enzymatically active.
Dynamic modelling provides a systematic framework to understand function in biological systems.
Therefore, it is important to understand functions of these conserved sHSPs of different organisms in future.
To explain this unexpected result and to understand functions of genes, it is necessary to analyze mRNA diversity.
Glands in the mandible and cloaca excrete oily chemicals that have a poorly understood function in communication.
S-layers have diverse but mostly poorly understood functions, but are known to act as virulence factors in Campylobacter and contain surface enzymes in Bacillus stearothermophilus.
HD-PTP, a Bro1 domain-containing protein, essential for early embryo development [8], has very poorly understood functions.
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