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Furthermore our study underscores the predictive power of three-dimensional culture to assess the pharmacological activity of drug combination.
Considering that we did not incorporate expression information of miRNAs, the establishment of such statistically detectable associations underscores the predictive potential of our approach.
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Our findings underscore the predictive value of comprehensive measures of functional limitations.
The process of identifying this predictive biomarker underscores the importance of activity characterization in a large set of molecularly annotated cancer cell lines and of collaborations between biostatisticians and molecular biologists.
These examples underscore the importance of rigid validation of the predictive accuracy of the models based on genetic profiles.
The dichotomy between what should be successful therapeutic targets and the ineffectiveness of drugs directed towards them underscores the critical importance of appropriate and predictive rodent models in the study of innovative therapies for the treatment of gliomas.
These data are supported by determination of PFS showing more favorable outcome in patients with decreased AGR2 mRNA levels, which underscores the importance of AGR2 as a predictive biomarker.
This finding underscores the significant role played by the variable age in model selection and in the predictive performance of the final model.
Moreover, the finding that the predictive significance of some prognostic factors changed following the introduction of a CD-20 monoclonal antibody, rituximab, underscores the necessity for revaluating the prognostic value of predictive factors after the introduction of rituximab [ 11, 12].
Finally, the modest proportion of variance explained by the logistic regression models (6 15%) underscores the need to study novel predictors and predictive models.
The predictive power was amazing.
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CEO of Professional Science Editing for Scientists @ prosciediting.com