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This perhaps underscores the function of human Dicer as a single-turnover enzyme specialized in generating mature miRNAs from a single cleavage reaction.
This also reveals a dominant role of Shh in the etiology of glucose metabolism in medulloblastoma and underscores the function of the Shh → E2F1 → PPARγ axis in altering substrate utilization patterns in brain cancers in favor of tumor growth.
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Molecular biology studies have underscored the function of oncogenes in glioblastoma progression, notably EGF, PDGF and their receptors, and a variety of tumour suppressor genes, particularly p16 INK4a, p14 ARF, PTEN, RB1 and TP53.
Functions which are not methods in a class should use either lowercase or lowercase with underscores (when the function name is a compound word).
Thus, loss of function studies underscores the divergent functions of HS1 and cortactin in different cell systems.
The variable penetrance seen in the DKO forelimbs, in which forelimb agenesis or profound limb malformation were seen, further underscores the crucial function of Esrps in limb development.
This underscores the different function of the small intestine (mainly uptake and transfer of nutrients) and the colon (mainly water absorption).
Most stakeholders underscore the dual function of Regenstein as study hall and research facility.
These results underscore the scaffolding function of Pdc1 and explain its importance for processing body formation.
13 Further, metastases downstream of the lung are associated with larger pulmonary tumors, and these findings underscore the filtering function of the lungs.
The downregulation of transcription was also seen for the sac3 R288D mutation, underscoring the critical function of this residue for highly inducible transcription.
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