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President Hamid Karzai spoke out about the girl's plight in a case that underscored the challenges of advancing women's rights here.
Experts said the results underscored the challenges of treating depression in people past retirement age who are buffeted by anxieties — about dying, losing friends, declining physical health — that are different from those of younger adult patients.
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Explaining the move, his lawyer, Nicholas Purnell, underscored the challenge of representing as bizarre and colorful a self-publicist as Jeffrey Archer, and told the court he hoped to keep the jury's attention on the evidence.
As the Obama administration took the first step Friday to regulate the drilling method known as fracking, opposition to the safety measures underscored the challenge of policing a practice that has cut U.S. dependence on foreign oil but raised fears of environmental damage and water contamination.
At the same time, it also underscored the challenge of finding ways to deal with a rapidly accelerating pace of change, in a world in which global phenomena like climate change affect children in increasingly unpredictable ways.
Senators John McCain and Barack Obama have said they would close the detention camp, but the review of the government's public files underscores the challenges of fulfilling that promise.
The experience of "4 Guys" underscores the challenges of creating and marketing theater, whose traditional audience is largely white, not only to different audiences but to the diversity within those audiences, the Latino one being a prime case in point.
The financial difficulties, which stem from a decline in corporate sponsorship and state financing in a weak economy, underscore the challenges of operating an orchestra in the shadow of New York City's musical offerings.
Further underscoring the challenges of providing humanitarian aid in Syria, where millions are displaced and needy, seven aid workers were abducted near the town of Saraqeb in the northern province of Idlib on Saturday.
For the revival of "Godspell," a 1971 musical based on parables from the Gospels, the director Daniel Goldstein and the show's composer and lyricist, Stephen Schwartz, have been tweaking language in some of the parables to underscore the challenges of group identity.
Even so, it underscores the challenges of overhauling banking supervision and regulation as Ben S. Bernanke, the current Fed chairman, has vowed to do, and comes as many in Congress are pushing to give the Fed even more responsibility for overseeing big financial companies.
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