Sentence examples for underscored due to from inspiring English sources

The contribution of immune system in lung fibrogenesis had been largely underscored due to the absence of response to immunosuppressive agents; however, the premise that lung fibrosis has an immunologic background has been recently revived.

The induction of genes involved in the unfolded-protein response underscored the cell stress due to enhanced energy metabolism.

In a subgroup of 24 MPM patients with bidimensionally measurable pleural lesions only, the discrepancy rate was 29%, always due to underscoring by RECIST.

However, when in the same subgroup the modified RECIST response evaluation was used the discrepancy rate was 21% and in all cases due to underscoring by WHO.

The percentage of patients in whom one or more discordance's between WHO and RECIST were detected was 47, 88% due to underscoring by RECIST.

On the other hand, creatinine alone may underscore the severity of AKI, due to its delayed increase in the setting of rapidly evolving AKI, especially in patients with fluid overload and hemodilution [ 10].

However, the poor control of micrometastases, declining operability, and the high incidence of long-term complications due to radiotherapy underscore the necessity for developing different therapeutic approaches, such as using an adjuvant CAM (complementary and alternative medicine) regimen for improved treatment outcomes [ 35].

These results suggest that a dual-gene combinatorial strategy could enhance the efficacy of gene therapy of DMD and underscored the importance of rAAV vectors due to their relative lack of immunologic and toxic side effect combined with their potential for body-wide systemic gene delivery to muscle [ 27].

Knockout mouse for Sod2 does not survive due to extensive cardiomyopathy underscoring the importance of O2− removal in normal cardiac function (Li et al., 1995).

Our findings, in combination with our recent study of congenital myasthenic syndrome due to DPAGT1 mutations, underscore the importance of N-linked protein glycosylation for proper functioning of the neuromuscular junction, indicate a mechanism that may underlie hypotonia in many of the CDGs and suggest appropriate treatment for the muscle weakness.

The significance of treatment discontinuation due to an IR is underscored by the fact that cetuximab is often administered to patients with disease progression following chemotherapy and thereby have limited treatment options.