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The underpinning models of the tow and matrix, (Tang et al., 2009) capture the physics of the interactions between fibres and matrix; and, in this way, permit modelling that bridges the length scales of the fibres and full-scale components.
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The realization of 'intelligent and resource aware' distributed enterprises requires substantial development of the underpinning modelling, information management and knowledge representation technologies.
The lack of an underpinning model also enables great flexibility, as the interactions between genes are not constrained to follow a parametric functional representation.
Successful extrapolation from rats to humans has been made for thiopental but the underpinning modelling was based on extensive prior knowledge of tissue kinetics [ 11].
This has the clear advantage that it provides a transparent link between parameter values and experimental data in comparison to alternative methods such as simplex optimisation [ 12], simulated annealing [ 13] and Levenberg-Marquart optimisation [ 14], which only provide parameter value estimates without increasing the understanding of the underpinning model mechanisms.
(Today, Haldex underpins models from Audi, Volvo, Ford and even the $2 million Bugatti Veyron).
For example, middle cerebral artery (MCA) stroke (a primary source of information that underpins models of language and aphasia) typically does not damage the inferior-to-middle aspects of the ATL, because it is in the posterior cerebral artery-MCA watershed territory (Phan et al. 2005, 2009).
Reasoning about graph and model transformation systems is an important means to underpin model-driven software engineering, such as Model-Driven Architecture (MDA) and Model Integrated Computing MICC).
The biochemical equations that underpin Model 3 are available as additional files.
Before they can do any good, the forecasters must go back to the drawing board, and ask themselves whether the theories of the economy underpinning their models are the right ones.
Equation 1 shows the Bayes' theorem, underpinning Bayesian models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com