Exact(2)
The lack of an underpinning model also enables great flexibility, as the interactions between genes are not constrained to follow a parametric functional representation.
This has the clear advantage that it provides a transparent link between parameter values and experimental data in comparison to alternative methods such as simplex optimisation [ 12], simulated annealing [ 13] and Levenberg-Marquart optimisation [ 14], which only provide parameter value estimates without increasing the understanding of the underpinning model mechanisms.
Similar(57)
Reasoning about graph and model transformation systems is an important means to underpin model-driven software engineering, such as Model-Driven Architecture (MDA) and Model Integrated Computing MICC).
The realization of 'intelligent and resource aware' distributed enterprises requires substantial development of the underpinning modelling, information management and knowledge representation technologies.
Successful extrapolation from rats to humans has been made for thiopental but the underpinning modelling was based on extensive prior knowledge of tissue kinetics [ 11].
The paper, which they continue to defend despite admitting mistakes, came under scrutiny after the pair released the spreadsheet calculations underpinning their model to rival academics at Massachusetts University.
The five factors underpinning the model are Openness to Experience, Conscientiousness, Extroversion, Agreeableness, and Neuroticism which combine to form the catchy acronym OCEAN.
The crucial normative ideal underpinning this model is liberal and cosmopolitan in orientation: all individuals deserve an equal chance to participate in the rule-making that governs their lives.
The formulae underpinning the model is given as; Let Y be a dichotomous variable which is defined as Y=left{begin{array}{c}hfill 1kern0.24em forkern0.24em subscribershfill hfill 0kern0.24em forkern0.24em nonmathit{hbox subscribershfill end{array}right.
JH contributed to the manuscript editing and developed the population equations underpinning the model.
This paper reviews his seminal experiments in detail and clarifies the often confusing concepts underpinning his model.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com