Treatment side effects and problems have potential to undermine adherence [28, 30], which may negatively impact disease management and outcomes [31]; treatment may be stressful, further reducing HRQOL.
Tension and fighting with a spouse can undermine adherence motivation when typically the very reason for accepting ARVs is to preserve the relationship.
10 Similarly, patient-related factors such as lack of transport, shortage of food, use of traditional medicine, alcohol abuse, depression, stigma and discrimination and lack of social support undermine adherence.
Lack of food security and poor nutritional status may hasten progression to AIDS-related illnesses, undermine adherence and response to antiretroviral therapy and exacerbate socioeconomic impacts of the virus [ 4].
Supporting the policy without critical reflection and comment by the health leadership may be indicative of disinterestedness that would ultimately undermine adherence to the policy, effectiveness of a health research system and the use of research findings for policy change and action.
We conclude that policy makers need to take heed of the social representations that govern patient-nurse relationships and their role in facilitating or undermining ART adherence.
The fear nurses can instill in patients and carers of child patients may lead them to delay going to the clinic for as long as possible, undermining ART adherence: They should at least have some courtesy or talk to the patients properly, because you end up being afraid of going back there.
Results: Consistent with hypotheses, curvilinear relationships between acceptance and denial with adherence were detected, suggesting that low levels of acceptance and high levels of denial undermine medication adherence.
For example, structural barriers in the public health system undermine medication adherence.
However, some patients cannot conform to these notions, leading to a breakdown in the relationship between nurses and patients, which can undermine ART adherence.
