This measure, called "data exclusivity," would undermine cost cutting generic competition by delaying the entry of generics to market.
Where multiple equilibrium prices occur for a single commodity because there are no wholesale markets, price transparency is undermined and transaction costs rise (the cost incurred by market participants in obtaining market information).
Unfortunately, the fire load is highly uncertain, which in turn undermine the cost effectiveness and reliability of the fire safety design of a whole structure when using the prescriptive-based fire safety design.
That may end up undermining the cost advantages of outsourcing, as the prices of raw materials and labour rise.In the long run, disruption to supply chains may be a huge strategic risk.
Creating and maintaining a program to measure outcomes can be so expensive that it undermines the cost effectiveness of value pricing.
Still Clarke responds, "To begin with, while it is our job to serve and protect in the most dangerous conditions, to have Dr. Potter undermine the cost of that sacrifice is reprehensible and entirely full of lies".
Given that the current highly effective drugs are substantially more expensive than previous antimalarials, the economic implications of overdiagnosis are considerable and undermine the cost effectiveness of the newer artemisinin based combination therapies (ACTs).
However, Sacramento recently decided to make permanent the subsidies it had been providing counties to handle their increased costs, undermining what this cost-shifting could have accomplished.
Cost-effectiveness or value of cardiovascular therapies may be undermined by unwarranted cost variation, particularly for heterogeneous procedures such as catheter ablation for atrial fibrillation (AF).
The Commission could see the act undermined by changing cost limits or allowing officials to include time spent "thinking about" answering a request for information in their cost limit calculation, among other proposals.
