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Sometimes there's nothing more relaxing than watching nubile chorines —with their underlying twinkle of humor and intelligence — gliding along contentedly in Berkeley's silver-screen sea.
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This mouse clearly proves that impaired Twinkle function is the underlying cause of mtDNA deletions and respiratory chain dysfunction and provides an excellent tool to study disease progression.
Underlying color.
Mutations in the mitochondrial helicase Twinkle underlie autosomal dominant progressive external ophthalmoplegia (PEO), as well as recessively inherited infantile-onset spinocerebellar ataxia and rare forms of mitochondrial DNA (mtDNA) depletion syndrome.
"Twinkle, Twinkle!" "Tickle Monster".
"TWINKLE, twinkle, little star".
Twinkle, twinkle little star...".
Another twinkle.
Twinkle toes, indeed.
C'mon, twinkle, twinkle, baby".
WHY do stars twinkle?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com