Sentence examples for underlying transformation from inspiring English sources

Carcinoma in situ (CIS) of the testis is considered to be a precancerous germinal cell lesion, but the precise cellular and molecular mechanisms underlying transformation of CIS into invasive pluripotent cancer cells remain to be elucidated.

Griffith (1928) transformed an attenuated and nonencapsulated Pneumococcus culture (type R) into a fully encapsulated and virulent Pneumococcus strains (type S) long before anyone knew that the material underlying transformation in Griffith's experiment was DNA (Avery et al. 1944) or how prokaryotes shuttle DNA from one cell to another.

A wide variety of murine model systems have been developed with the aim of not only evaluating novel therapeutics, but also examining the mechanisms underlying transformation, invasion and metastasis in human tumours with a view to better study prevention and screening as well as diagnostic and treatment strategies.

In this paper, we propose a theoretical explanation for this difference: we show that the recoverable strain in a polycrystal depends on the texture of the polycrystal, the transformation strain of the underlying martensitic transformation and especially on the change of symmetry during the underlying transformation.

They are a key link in the development of service programs and the achievement of underlying transformations.

Study findings are important in light of changes unfolding in some Arab countries and can help undertake an analysis of underlying transformations and their respective health policy implications including the way evidence will be used in policy decisions.

Also, they can provide a baseline to undertake an analysis of the underlying transformations and their respective health policy implications including the way evidence will be used in the future into policy decisions.

Also, the underlying phase transformation is called martensitic, after a similar transformation in rapidly quenched steel to a phase known as martensite.

Having this information may contribute to shed more light on the mechanisms underlying headache transformation.

Genome-wide DNA hypomethylation is a critical mechanism underlying neoplastic transformation.

This paper assesses three key factors underlying this transformation: public policies and regulations, urban infrastructure, and knowledge creation and utilisation.