Sentence examples for underlying this resistance from inspiring English sources

There is limited understanding of the mechanisms underlying this resistance.

What may be the potential mechanisms underlying this resistance?

Thus, a better understanding of the mechanism(s) underlying this resistance might pave the way towards more effective strategies.

We need to understand the molecular determinants regulating ER DNA binding and activity to elucidate the mechanisms underlying this resistance.

Due to the complexity of the highly interconnected hormonal signaling networks targeted by WRKY33, the precise molecular mechanisms underlying this resistance remain to be fully elucidated.

However, their use remains limited because of the rapid development of MDR; thus, it is necessary to explore the mechanisms underlying this resistance.

The conduct problems of children with callous-unemotional (CU) traits (i.e., lack of empathy, lack of guilt/lack of caring behaviors) are particularly resistant to current behavioral interventions, and it is possible that differential sensitivities to punishment and reward may underlie this resistance.

Resistance has been attributed to elevated activities of cytochrome P450s but the molecular basis underlying this metabolic resistance is unknown.

However, the mechanisms underlying this major resistance trait of A. cerana are unknown.

To identify potential mechanisms underlying this inherent resistance phenomenon, we performed pathway-centric, gain-of-function screens in JAK2 V617F) hematopoietic cells and found that the activation of the guanosine triphosphatase (GTPase) RAS or its effector pathways [mediated by the kinases AKT and ERK (extracellular signal-regulated kinase)] renders cells insensitive to JAK inhibition.

A study performed about 40 years ago showed that the biochemical mechanism underlying this mercurial resistance is based on the enzymatic degradation of organomercurials and the subsequent reduction of the resulting mercuric ions to the less toxic and more volatile metallic mercury (Tonomura et al. 1968).