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It is also clear that very little is known about the mechanisms underlying this event.
We believe that the mechanisms underlying this event are much like those underlying CSD and other SD-like phenomena in mammals and a conserved genetic component to this thermotolerance pathway in insects has recently been demonstrated [35].
The molecular mechanisms underlying this event are only partly understood.
Although 90% of cancer deaths are caused by metastasis, the pathogenesis and mechanisms underlying this event remain poorly defined [ 18].
Nuclear Foxo3a shift after treatments occurred in MCF-7 and MDA-MB-231 cells independent of AKT inactivation, but the molecular mechanisms underlying this event need to be further investigated.
Even though we have not determined the exact mechanisms underlying this event, we demonstrated that BCG adhesion and internalisation is higher for sTn-positive cells in vitro, further reinforcing tumour findings.
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In an effort to elucidate the molecular events underlying this result, we applied exonuclease III (Exo III) in conjunction with a SCGE assay, enabling detection of DNA-AP sites along the genome.
Initially discovered in response to task-relevant, infrequent oddball stimuli [19] and found to be sensitive to the subjective probability assigned to the occurrence of the eliciting event [20], many cognitive mechanism models underlying this neural event have been proposed [21 24].
To assess whether the activity of these proteins is implicated in the changes in cell behaviour underlying this morphogenetic event, we expressed DN forms of Rab5 and Rab11 separately in the AS and the epidermis to block endocytosis (Rab5) and recycling (Rab11).
Ascertainment of the mechanisms underlying this deacetylation event likely will require the use of different models.
In spite of the importance of E6 intron splicing in the production of E7, the regulatory mechanism underlying this splicing event remains largely unexplored.
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CEO of Professional Science Editing for Scientists @ prosciediting.com