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In all, our data provide direct evidence that CPEB3 is a functional prion in the mammalian brain and underline the potential importance of an actin/CPEB3 feedback loop for the synaptic plasticity underlying the persistence of long-term memory.
To understand the reasons underlying the persistence of the high levels of PM10 in the Delhi region, a novel experiment was designed by appropriating a well-known tracer-source Diwali fireworks—emitracer-source Diwali ofireworkslatemitting (PM) in the atmosphere.
Our results provide novel insights into the mechanisms underlying the persistence of species in highly fragmented areas.
A better understanding of the interplay between these two classes of genetic factors may reveal the logic underlying the persistence of psychosis, and point to the solution of one of the most fascinating puzzles of evolutionary psychology.
To investigate the mechanisms underlying the persistence of a large proportion of methylation peaks induced by Dex, we focused our investigation on the genes mediating epigenetic effects.
Plaque hemorrhage and inflammatory cell delivery are the key mechanisms underlying the persistence of chronic vascular inflammation and the rapid expansion or rupture of atherosclerotic plaques [ 28, 29].
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Genomic signals such as enhancers, silencers, and repetitive DNA, while required for the establishment of alternative chromatin states, have an unclear role in epigenetic processes that underlie the persistence of chromatin states throughout development.
Fear of change often underlies the persistence of falling out of love.
Because the head tissues were collected 24 hr after training, we hypothesize that many of the genes for which we detected differential gene expression contribute to lasting changes in neural circuitry that underlies the persistence of long-term courtship suppression beyond 24 hr.
Understanding the factors underlying the historical persistence or replacement of particular sub-populations of M. tuberculosis has potential relevance for predicting future trends in disease epidemiology.
Although telomere lengthening and telomerase activity have been linked to CTL function and persistence [17], [18], [19], the molecular mechanisms underlying the lack of persistence of the tumor-reactive CTLs in the tumor microenvironment is largely unknown.
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Justyna Jupowicz-Kozak
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