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The markers may provide an insight to the potential mechanisms underlying the pathophysiology of BD.
This lack of benefit could be due to the lingering central sensitization underlying the pathophysiology of MOH [17].
Based on the phenomenon of hypoperfusion in the event of a headache, the vessel constriction hypothesis was proposed including two potential physiological mechanisms underlying the pathophysiology of CC.
The neural circuits underlying the pathophysiology of mood disorders mostly include the prefrontal cortex and anatomically related limbic structures (Price and Drevets 2012).
The molecular events underlying the pathophysiology of CH are unknown because of the lack of valuable experimental animal model, and, therefore the treatment is largely based on empirical evidence [6].
Critical to the success of this endeavor will be the development of behavioral assays and animal models of ASD that can provide researchers with experimental systems that enable investigation into specific mechanisms underlying the pathophysiology of ASD.
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Dysregulation of glycogen synthase kinase-3-beta (GSK-3β) signaling pathways is thought to underlie the pathophysiology of mood disorders.
Neurochemical imbalance between noradrenergic and serotonergic systems has been postulated to underlie the pathophysiology of psychiatric illnesses involving mood disorders.
Functional imaging studies indicate that imbalances in cortico-limbic activity and connectivity may underlie the pathophysiology of MDD.
Cortical spreading depression (CSD), believed to underlie the pathophysiology of migraine aura[3], would be expected to influence sensory responses of thalamic neurons, through such corticothalamic interactions.
Disease modifying pharmacological treatment suppresses the underlying progression of a disease by intervening in the biological processes that underlie the pathophysiology of the disease that leads to cell death and/or dysfunction.
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